Maharishi Vedic herbal formulations have been found to protect against tissue damage caused by the chemical solvent toluene, which is a potent inducer of free radicals and important industrial health risk. Biochemical Archives, 1994; 10:25-31; Free Radicals in Biology and Medicine 1995, 18: 687-697; Pharmacology, Biochemistry & Behavior 1994, 48(2): 505-510.
Cancer and Protection against Toxic Effects of Cancer Chemotherapy
Protection against cancer (animal research). In studies on laboratory animals, herbal compounds used in Maharishi Ayurveda reduced the development, growth, spread, and mortality of cancer. In one series of experiments, an herbal supplement used in Maharishi Ayurveda provided up to 88 percent protection against carcinogen-induced breast cancer, with effects during both promotion and initiation phases of carcinogenesis. Also, 60 percent of the control animals that had developed fully formed tumors showed tumor regression when their diet was subsequently supplemented with the herbal compound. In 50 percent of these animals, the tumors regressed completely. Pharmacology, Biochemistry, and Behavior 1990, 35: 767-773; European Journal of Pharmacology 1990, 183: 193; Nutritional Research 1992, 12: 51-61; Journal of Research and Education in Indian Medicine 1991, 10(3): 1-8.
Reduction in cancer metastases (animal research). This study showed significant reduction in number and size of metastatic nodules in mice with a rapidly metastasizing form of lung cancer using a Maharishi Vedic herbal supplement. Nutritional Research 1992, 12: 667-676.
Reversal of malignant process (in vitro). Studies showed that a Maharishi Vedic herbal supplement reversed morphological and biochemical changes associated with malignancy in neuroblastoma cells in culture. Neuropharmacology 1992, 31: 599-607.
Inhibition of malignant transformation (in vitro). Laboratory studies reported by the chemopreventive branch of the National Cancer Institute indicated that a Maharishi Vedic herbal supplement inhibits processes of malignant transformation in animal epithelial cells and human lung tumor cells. Proceedings of the American Association of Cancer Research 1991, 32: 128.
Reduced toxic effects of cancer chemotherapy (human study). This controlled prospective study of a Maharishi Vedic herbal supplement was conducted on people receiving combination chemotherapy for various types of cancer, including non-Hodgkin’s lymphoma, ovarian cancer, breast cancer, oral cancer, and osteogenic sarcoma. Chemotherapeutic agents included cyclophosphamide, vincristine, methotrexate, doxorubicin, prednisone, cisplatinum, adriamycin, and 5-fluorouracil. The study found significant reductions in toxic effects of chemotherapy, including reduced vomiting and diarrhea, and improvements in sleep, weight, and overall well-being compared to control patients. In addition, patients taking the herbal preparation showed reduced free radical activity and decreased hematological toxicity, as measured by maintenance of higher leukocyte and platelet counts, compared to the control group. Proceedings of the Sixteenth International Cancer Congress 1994, Vol. 1., pp 3099-3102. Bologna, Italy: Monduzzi Editore.
Protection against toxic effect of chemotherapy.
A Maharishi Vedic herbal supplement was found to enhance the in vitro activity of the glutathione anti-oxidant system, which provides a vital natural defense against toxins. Further investigation showed that the herbal compound also prevented toxic effects of the chemotherapeutic agent cisplatin on this system, enhancing liver and kidney glutathione (gsh) and glutathione-s-transferase (gst) activity.
Proceedings of the XVI International Cancer Congress, 1994, Vol.1, pp 589-592. Bologna, Italy: Monduzzi Editore. Reduced toxic effects of chemotherapy (animal research). Maharishi Vedic herbal supplements significantly reduced cardiotoxicity and mortality caused by the chemotherapeutic drug adriamycin. Biochemical Archives 1992; 8: 267-272.